Description

6-(Glucosamine)-6-Deoxy-β-Cyclodextrin is a chemically modified cyclodextrin derivative where a glucosamine moiety is introduced at the 6-position of the glucose unit, creating a unique host molecule with enhanced molecular recognition properties. This modification is significant as it imparts both the cavity encapsulation capability of β-cyclodextrin and the biofunctional, often cationic, characteristics of glucosamine, making it a powerful tool for solubility enhancement, chiral separation, and targeted delivery. It is primarily needed by researchers and manufacturers in the pharmaceutical, biotechnology, and advanced material science sectors for developing novel drug formulations, separation media, and sensor technologies.

Application

• Pharmaceutical Solubility & Bioavailability Enhancement: Acts as a complexing agent to improve the aqueous solubility, stability, and bioavailability of poorly soluble active pharmaceutical ingredients (APIs).
• Chiral Separation & Analysis: Serves as a chiral selector or stationary phase modifier in capillary electrophoresis (CE) and high-performance liquid chromatography (HPLC) for the separation of enantiomers.
• Drug Delivery Systems: Utilized in the design of novel drug delivery carriers, such as nanoparticles and hydrogels, for controlled and targeted release, leveraging its biocompatibility and host-guest chemistry.
• Biomimetic Catalysis & Enzyme Modeling: Functions as an enzyme mimic or a component in artificial enzyme systems due to its tailored cavity and functional group.
• Chemical Sensor Development: Employed as a recognition element in sensor designs for the selective detection of specific organic molecules, ions, or gases.
• Cosmetic & Personal Care Formulations: Used to stabilize fragrances, vitamins, or other active ingredients in creams and lotions, and to reduce irritation.

Basic Information

Product Name	6-(Glucosamine)-6-Deoxy-β-Cyclodextrin
CAS No.	1035870-91-7
Molecular Formula	C48H82N1O40
Molecular Weight	1241.15 g/mol
Synonyms	6-Glucosamino-6-deoxy-β-cyclodextrin; 6A-Amino-6A-deoxy-β-cyclodextrin glucosamine conjugate; Mono(6-glucosamino-6-deoxy)-β-cyclodextrin; β-Cyclodextrin, 6-(glucosamine)-6-deoxy-; Heptakis(6-O-glucosamino-6-deoxy)-β-cyclodextrin (related polymer); Glucosamine-modified β-cyclodextrin; 6-NH2-β-CD glucosamine derivative
EINECS	Contact for details

Quality Control

Our 6-(Glucosamine)-6-Deoxy-β-Cyclodextrin is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) that includes results for assay, impurity profile, and other critical parameters. Specifications can be aligned with research-grade or pharmaceutical development requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a low-humidity environment when possible to prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details
Bacterial Endotoxins	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.