Description

9-Ing-41 is a potent and selective small molecule inhibitor of casein kinase 2 (CK2), a serine/threonine kinase implicated in numerous cellular processes. This compound matters for researchers and developers as it provides a critical tool for modulating key signaling pathways involved in cell growth, proliferation, and survival. It is primarily needed by pharmaceutical R&D teams, academic researchers, and biotechnology companies focused on oncology, neurodegenerative diseases, and inflammatory disorders.

Application

• Biochemical Research: A key reagent for studying CK2-mediated signaling pathways, protein phosphorylation, and cellular regulation in vitro.
• Drug Discovery & Development: Used as a lead compound or reference standard in high-throughput screening and preclinical studies for cancer therapeutics.
• Oncology Research: Investigated for its potential to inhibit tumor cell proliferation and induce apoptosis in various cancer cell lines.
• Neurodegenerative Disease Models: Employed in research exploring the role of CK2 in conditions like Alzheimer's and Parkinson's disease.
• Inflammation and Immunology Studies: Used to probe CK2 function in immune cell signaling and inflammatory responses.
• Cell Biology Assays: Serves as a specific inhibitor to elucidate the biological functions of CK2 in cell cycle control and DNA damage response.

Basic Information

Product Name	9-Ing-41
CAS No.	1034895-42-5
Molecular Formula	C₂₀H₁₉N₅O₂
Molecular Weight	361.40 g/mol
Synonyms	9ING41; 9-ING-41; (E)-N-(4-((3-(Pyridin-4-yl)-1H-pyrazol-1-yl)methyl)phenyl)-3-(quinolin-6-yl)acrylamide; CK2 Inhibitor 9-ING-41; Casein Kinase II Inhibitor 9-ING-41; GSK-3 Inhibitor XIII; 9ING-41; 9-ING 41
EINECS	Contact for details

Quality Control

Our 9-Ing-41 is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability. Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Off-white to yellow solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Consistent with molecular weight
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.