Description

(5-Chloro-2-Fluoropyridin-4-Yl)Boronic Acid is a high-value, multi-functional boronic acid derivative, serving as a critical building block in modern synthetic chemistry. Its core value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients, and in materials science for creating advanced functional polymers and electronic materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Building block for creating novel herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Material Science: Used in the development of organic light-emitting diodes (OLEDs), liquid crystal displays (LCDs), and other advanced electronic materials.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for exploring new synthetic pathways and creating compound libraries.
• Ligand Synthesis: Serves as a precursor for synthesizing specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Bioconjugation: Potential use in bioconjugation chemistry for labeling biomolecules due to its reactive boronic acid group.

Basic Information

Product Name	(5-Chloro-2-Fluoropyridin-4-Yl)Boronic Acid
CAS No.	1034659-38-5
Molecular Formula	C5H4BClFNO2
Molecular Weight	175.36 g/mol
Synonyms	5-Chloro-2-fluoro-4-pyridineboronic acid; (5-Chloro-2-fluoropyridin-4-yl)boronic acid; 4-Borono-5-chloro-2-fluoropyridine; 5-Chloro-2-fluoro-4-pyridinylboronic acid; 2-Fluoro-5-chloro-4-pyridineboronic acid; B-(5-Chloro-2-fluoro-4-pyridinyl)boronic acid; 1034659-38-5
EINECS	Contact for details

Quality Control

Our (5-Chloro-2-Fluoropyridin-4-Yl)Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistent performance for sensitive applications like pharmaceutical synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.