Description

2,5-Dibromo-4-Fluoropyridine is a high-purity halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring bromine and fluorine substituents, makes it an invaluable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, leveraging its halogenated pyridine core.
• Material Science Precursor: Serves as a monomer or functionalization agent in the synthesis of specialty polymers, liquid crystals, and electronic materials.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions due to the presence of bromine atoms.
• Ligand and Catalyst Development: Employed in the design and synthesis of novel ligands for transition metal catalysis and organocatalysts.
• Chemical Research & Development: A versatile reagent for medicinal chemistry, process chemistry, and general organic synthesis in R&D laboratories.

Basic Information

Product Name	2,5-Dibromo-4-Fluoropyridine
CAS No.	1033203-46-1
Molecular Formula	C5H2Br2FN
Molecular Weight	274.88 g/mol
Synonyms	4-Fluoro-2,5-dibromopyridine; 2,5-Dibromo-4-fluoropyridine; 4-Fluoro-2,5-dibromopyridine; Pyridine, 2,5-dibromo-4-fluoro-; 2,5-Dibromo-4-fluoro-pyridine; 1033203-46-1; 4-Fluor-2,5-dibrompyridin
EINECS	Contact for details

Quality Control

Our 2,5-Dibromo-4-Fluoropyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.