Description

2-Cyano-3-Nitro-5-Fluoropyridine is a high-value, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its molecular structure, featuring cyano, nitro, and fluoro substituents on a pyridine core, makes it a versatile intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system, oncology, and anti-infective therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the fluorine atom can enhance biological activity and environmental stability.
• Material Science: Serves as a building block for advanced organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in organic semiconductors.
• Chemical Synthesis: Utilized in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution reactions due to its reactive halogen and nitro groups.
• Ligand and Catalyst Development: The pyridine nitrogen and substituents make it a candidate for designing novel chelating ligands in coordination chemistry and catalysis.

Basic Information

Product Name	2-Cyano-3-Nitro-5-Fluoropyridine
CAS No.	1033202-51-5
Molecular Formula	C6H2FN3O2
Molecular Weight	167.10 g/mol
Synonyms	5-Fluoro-3-nitropyridine-2-carbonitrile; 3-Nitro-5-fluoropyridine-2-carbonitrile; 2-Cyano-5-fluoro-3-nitropyridine; 5-Fluoro-2-cyano-3-nitropyridine; 2-Pyridinecarbonitrile, 5-fluoro-3-nitro-; 1033202-51-5
EINECS	Contact for details

Quality Control

We maintain a rigorous quality management system to ensure batch-to-batch consistency and high purity. Our standard grade for 2-Cyano-3-Nitro-5-Fluoropyridine typically meets a purity specification of ≥97% (HPLC), with stringent control of related substances and residual solvents. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound should be kept under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Maximum Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.