Description

sec-Butylmagnesium Chloride - Lithium Chloride is a highly reactive organometallic reagent complex, specifically formulated as a Grignard reagent stabilized with lithium chloride. This complex offers superior reactivity and selectivity compared to traditional Grignard reagents, making it a critical component for advanced chemical synthesis. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the formation of carbon-carbon bonds and the introduction of the sec-butyl group into complex molecular frameworks.

Application

• Pharmaceutical Intermediate Synthesis: Key reagent for constructing carbon skeletons and introducing the sec-butyl moiety in active pharmaceutical ingredient (API) development.
• Agrochemical Manufacturing: Used in the synthesis of herbicides, fungicides, and other crop protection agents requiring specific alkyl chain modifications.
• Fine Chemical Production: Enables precise alkylation and coupling reactions in the manufacture of flavors, fragrances, and advanced materials.
• Polymer Chemistry: Serves as an initiator or chain-transfer agent in the synthesis of specialized polymers and co-polymers.
• Academic & Industrial R&D: A fundamental tool for methodological development in organic synthesis and catalysis research.
• Nucleophilic Addition Reactions: Efficiently adds to carbonyl compounds (aldehydes, ketones, esters) to produce secondary and tertiary alcohols.

Basic Information

Product Name	sec-Butylmagnesium Chloride - Lithium Chloride
CAS No.	1032768-06-1
Molecular Formula	C4H9ClMg · LiCl
Molecular Weight	Contact for details
Synonyms	sec-Butylmagnesium Chloride Lithium Chloride Complex; Lithium Chloride sec-Butylmagnesium Chloride Adduct; Magnesium, chlorosec-butyl-, compd. with lithium chloride (1:1); sec-BuMgCl·LiCl; 1-Methylpropylmagnesium Chloride - Lithium Chloride; Grignard Reagent sec-C4H9MgCl·LiCl; sec-Butyl Grignard Reagent with LiCl
EINECS	Contact for details

Quality Control

Our sec-Butylmagnesium Chloride - Lithium Chloride complex is manufactured under stringent quality control protocols to ensure batch-to-batch consistency and high reactivity. Each lot is analyzed to confirm concentration (typically supplied as a solution in THF or diethyl ether), purity, and absence of protic impurities. A comprehensive Certificate of Analysis (COA) detailing assay (by titration), solvent content, and other critical parameters is provided with every shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. This product is hygroscopic (moisture-sensitive) and easily oxidized; it must be stored under an inert atmosphere (argon or nitrogen) in a cool, dry, and well-ventilated area. For solutions, store at room temperature (15-25°C) or as specified on the label. Keep away from heat, sparks, open flames, and incompatible materials such as water, alcohols, and strong acids.

Specification

Item	Specification
Appearance	Colorless to slightly yellow solution
Concentration (in THF)	0.5 M, 1.0 M, or 2.0 M (Custom concentrations available)
Assay (Titration)	≥ 95%
Identification (IR/NMR)	Conforms to structure
Water Content (Karl Fischer)	< 100 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.