Description

3-(1,1-Difluoroethyl)Benzaldehyde is a high-purity fluorinated aromatic aldehyde building block. This compound is valued for its unique difluoroethyl substituent, which imparts specific electronic and steric properties critical for advanced synthesis. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients. The product is supplied to meet the stringent requirements of modern organic and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in creating molecules with enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluorine atoms can improve lipophilicity and biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and material science applications.
• Functional Material Research: Employed in the synthesis of monomers and building blocks for advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Useful for synthesizing tagged molecules and probes for studying biological mechanisms and target engagement.

Basic Information

Product Name	3-(1,1-Difluoroethyl)Benzaldehyde
CAS No.	1032527-37-9
Molecular Formula	C9H8F2O
Molecular Weight	170.16 g/mol
Synonyms	m-(1,1-Difluoroethyl)benzaldehyde; 3-(1,1-Difluoroethyl)benzaldehyde; Benzaldehyde, 3-(1,1-difluoroethyl)-; 1,1-Difluoro-1-(3-formylphenyl)ethane; 3-(α,α-Difluoroethyl)benzaldehyde
EINECS	Contact for details

Quality Control

Our 3-(1,1-Difluoroethyl)Benzaldehyde is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chromatographic purity analysis and structural confirmation, to ensure it meets the high standards required for research and scale-up activities. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided for full traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere for long-term preservation. Keep away from strong bases and reducing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.