Description

(2-Fluoro-4-Methylpyridin-3-Yl)Boronic Acid is a high-value boronic acid derivative and a versatile building block in modern synthetic chemistry. Its core value lies in enabling the precise construction of complex molecules through reliable cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially in kinase inhibitor and CNS-active compound research.
• Agrochemical Synthesis: Used to create advanced pyridine-based herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Material Science: Serves as a monomer or functionalization agent in the development of organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Biology & Proteomics: Employed as a handle for bioconjugation and the development of molecular probes and activity-based protein profiling (ABPP) reagents.
• Ligand Synthesis: Acts as a building block for creating novel bidentate and tridentate ligands used in catalysis and metal-organic frameworks (MOFs).
• Custom Synthesis & Contract Manufacturing: Supplied to CROs and CDMOs for bespoke synthesis projects requiring specific fluorinated pyridine motifs.

Basic Information

Item	Details
Product Name	(2-Fluoro-4-Methylpyridin-3-Yl)Boronic Acid
CAS No.	1029654-30-5
Molecular Formula	C6H7BFNO2
Molecular Weight	154.94 g/mol
Synonyms	2-Fluoro-4-methylpyridine-3-boronic acid; (2-Fluoro-4-methyl-3-pyridinyl)boronic acid; 3-Borono-2-fluoro-4-methylpyridine; 2-Fluoro-4-methyl-3-pyridylboronic acid; Boronic acid, B-(2-fluoro-4-methyl-3-pyridinyl)-; 1029654-30-5
EINECS	Contact for details

Quality Control

Our (2-Fluoro-4-Methylpyridin-3-Yl)Boronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.