Description

2-Chloro-4-Phenylpyridine-3-Boronic Acid is a versatile and high-value boronic acid derivative, serving as a critical building block in modern synthetic chemistry. Its core value lies in its role as a key coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl and heterobiaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of drug candidates, especially those containing biphenyl or phenylpyridine scaffolds for oncology, CNS, and antiviral applications.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific phenylpyridine motifs.
• Material Science Research: Employed in the development of organic light-emitting diodes (OLEDs), liquid crystals, and conductive polymers due to its ability to form conjugated systems.
• Chemical Biology & Proteomics: Acts as a handle for bioconjugation and the development of molecular probes and inhibitors targeting specific enzymes or proteins.
• Catalyst Ligand Precursor: Can be utilized to synthesize novel bidentate or tridentate ligands for transition metal catalysis.
• Custom Synthesis & Contract Manufacturing: Supplied to CROs and CDMOs for client-specific projects requiring advanced boronic acid chemistry.

Basic Information

Product Name	2-Chloro-4-Phenylpyridine-3-Boronic Acid
CAS No.	1029654-25-8
Molecular Formula	C11H9BClNO2
Molecular Weight	233.46 g/mol
Synonyms	(2-Chloro-4-phenylpyridin-3-yl)boronic acid; 2-Chloro-4-phenyl-3-pyridineboronic acid; 3-Borono-2-chloro-4-phenylpyridine; 1029654-25-8; 2-Chloro-4-phenylpyridine-3-boronic acid pinacol ester (protected form); 2-Chloro-4-phenyl-3-pyridinylboronic acid
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-Phenylpyridine-3-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with stringent industry standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.