Description

Nvp Cxcr2 20 is a potent and selective small molecule antagonist of the C-X-C chemokine receptor type 2 (CXCR2). This compound is a critical research tool for investigating the role of the CXCR2 signaling pathway in inflammatory and oncological processes. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and biotechnology companies engaged in drug discovery and mechanistic studies. The product is supplied under strict quality control to ensure reliable and reproducible experimental results.

Application

• Drug Discovery Research: Used as a reference standard and pharmacological tool in the development of novel anti-inflammatory and anti-cancer therapeutics targeting the CXCR2 receptor.
• Inflammatory Disease Models: Applied in preclinical studies to elucidate the mechanisms of diseases such as chronic obstructive pulmonary disease (COPD), rheumatoid arthritis, and psoriasis.
• Oncology Research: Employed to study the role of CXCR2 in tumor microenvironment modulation, angiogenesis, and cancer cell metastasis.
• Signal Transduction Studies: Serves as a selective inhibitor to dissect the CXCR2-mediated signaling cascades in various cell types, including neutrophils and epithelial cells.
• Biomarker Development: Utilized in assay development for screening and validating potential biomarkers associated with CXCR2 pathway activity.

Basic Information

Product Name	Nvp Cxcr2 20
CAS No.	1029521-30-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	NVP-CXCR2-20; CXCR2 Antagonist 20; Chemokine Receptor CXCR2 Inhibitor; 1029521-30-9; (Compound name based on internal research code)
EINECS	Contact for details

Quality Control

Our Nvp Cxcr2 20 is manufactured and handled under a quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for research-grade chemicals. A comprehensive Certificate of Analysis (COA) detailing purity (typically by HPLC), identity confirmation (e.g., by MS, NMR), and other relevant parameters is provided with every shipment to guarantee traceability and support your research integrity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.