Description

3-Bromo-4-Methylbenzene-1-Sulfonyl Chloride is a versatile and highly reactive organosulfur compound, serving as a critical building block in advanced organic synthesis. Its value lies in the sulfonyl chloride functional group, which readily undergoes nucleophilic substitution to form sulfonamides and sulfonate esters, enabling the construction of complex molecular architectures. This intermediate is essential for researchers and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used to create novel sulfonylurea or sulfonamide herbicides and pesticides with specific biological activity.
• Material Science: Building block for functional polymers and advanced materials requiring sulfonated moieties for specific properties like ion exchange.
• Chemical Research: A valuable reagent in medicinal chemistry and process development for introducing the sulfonyl group into target molecules.
• Dye and Pigment Manufacturing: Intermediate in the production of specialized sulfonated dyes and colorants.

Basic Information

Item	Detail
Product Name	3-Bromo-4-Methylbenzene-1-Sulfonyl Chloride
CAS No.	1029145-99-0
Molecular Formula	C7H6BrClO2S
Molecular Weight	269.54 g/mol
Synonyms	3-Bromo-4-methylbenzenesulfonyl chloride; 2-Bromo-4-methylbenzenesulfonyl chloride; 4-Methyl-3-bromobenzenesulfonyl chloride; 3-Bromo-p-toluenesulfonyl chloride; 2-Bromo-4-methylbenzene-1-sulfonyl chloride; (3-Bromo-4-methylphenyl)sulfonyl chloride; 3-Bromo-4-methylphenylsulfonyl chloride; 3-Bromo-4-methylbenzenesulphonyl chloride
EINECS	Contact for details

Quality Control

Our 3-Bromo-4-Methylbenzene-1-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at 2-8°C (refrigerated) or as specified on the label. Due to its hygroscopic and moisture-sensitive nature, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.