Description

Retreversine is a potent and selective small molecule inhibitor with significant research applications in cell biology and regenerative medicine. This compound is valued for its ability to induce dedifferentiation in somatic cells, making it a critical tool for studying cellular reprogramming and plasticity. It is primarily utilized by researchers and developers in the pharmaceutical, biotechnology, and academic sectors for advanced life science research and drug discovery initiatives.

Application

• Cellular Reprogramming Research: Used as a key reagent to study the mechanisms of dedifferentiation and the generation of induced pluripotent stem cells (iPSCs).
• Regenerative Medicine Studies: Investigated for its potential to enhance tissue repair and regeneration by modulating cell fate.
• Drug Discovery Screening: Serves as a reference compound or a pharmacologic tool in high-throughput screening assays targeting cell cycle and differentiation pathways.
• Oncology Research: Employed in studies exploring cancer cell plasticity, epithelial-mesenchymal transition (EMT), and tumor initiation.
• Biochemical Pathway Analysis: A tool for elucidating signaling pathways involved in cell growth, division, and specialization.
• Academic and Institutional R&D: Essential for basic research in universities and institutes focusing on developmental biology and stem cell technology.

Basic Information

Product Name	Retreversine
CAS No.	1028332-91-3
Molecular Formula	C₂₀H₂₀N₆O₂
Molecular Weight	376.41 g/mol
Synonyms	1-(4-Methyl-2-pyridinyl)-3-(4-pyridinyl)-2-imidazolidinone; 1-(4-Methylpyridin-2-yl)-3-(pyridin-4-yl)imidazolidin-2-one; Retreversine; DYRK Inhibitor; Dedifferentiation Inducer; Stem Cell Reprogramming Compound; Research Compound 1028332-91-3
EINECS	Contact for details

Quality Control

Our Retreversine is manufactured under strict quality management systems to ensure high purity and batch-to-batch consistency. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for research-grade chemicals, ensuring reliable performance for your critical experiments. Certificates of Analysis are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.