Description

3-Fluoro-5-Iodobenzotrifluoride is a high-value, multi-functional halogenated aromatic building block. This compound is engineered to provide a versatile trifluoromethylated core with orthogonal halogen handles for advanced coupling and functionalization reactions. It is essential for researchers and process chemists in the pharmaceutical and agrochemical industries who require precise, reliable intermediates for the synthesis of complex molecules, including active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and pesticides, leveraging the stability imparted by the trifluoromethyl group.
• Liquid Crystal & OLED Materials: Serves as a precursor in the production of fluorinated components for electronic display materials and organic light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: The iodine and fluorine substituents make it an excellent substrate for Suzuki, Sonogashira, and Buchwald-Hartwig cross-coupling reactions to create complex biaryl structures.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new synthetic methodologies and creating specialized chemical libraries.
• Fluorine Chemistry: Acts as a critical intermediate for introducing fluorine atoms and trifluoromethyl groups into more complex molecular architectures.

Basic Information

Product Name	3-Fluoro-5-Iodobenzotrifluoride
CAS No.	1027513-14-9
Molecular Formula	C7H2F4I
Molecular Weight	303.99 g/mol
Synonyms	1-Fluoro-3-iodo-5-(trifluoromethyl)benzene; 3-Iodo-5-fluorobenzotrifluoride; 5-Fluoro-3-iodobenzotrifluoride; 3-Fluoro-5-iodo-alpha,alpha,α-trifluorotoluene; Benzene, 1-fluoro-3-iodo-5-(trifluoromethyl)-; α,α,α-Trifluoro-3-fluoro-5-iodotoluene
EINECS	Contact for details

Quality Control

Our 3-Fluoro-5-Iodobenzotrifluoride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures material consistency and reliability for your critical research and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.