Description

3-Bromo-5-Chloro-2-Iodobenzotrifluoride is a high-value, multi-halogenated aromatic building block essential for advanced organic synthesis. Its unique trifluoromethyl and halogen substitution pattern makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, material science, and ligand development.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of fluorine-containing drug candidates.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and pesticides where the halogenated aromatic core provides bioactivity.
• Material Science Precursor: Serves as a monomer or functionalization agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An excellent substrate for various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira, Heck) due to the presence of bromo and iodo leaving groups.
• Ligand and Catalyst Development: Utilized in the design and synthesis of novel ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Research & Development: A versatile reagent for exploring new synthetic methodologies and constructing complex molecular architectures in academic and industrial labs.

Basic Information

Product Name	3-Bromo-5-Chloro-2-Iodobenzotrifluoride
CAS No.	1027512-75-9
Molecular Formula	C7H2BrClF3I
Molecular Weight	399.35 g/mol
Synonyms	2-Iodo-3-bromo-5-chlorobenzotrifluoride; 1-Bromo-3-chloro-5-iodo-2-(trifluoromethyl)benzene; 3-Bromo-5-chloro-α,α,α-trifluoro-2-iodotoluene; Benzene, 1-bromo-3-chloro-5-iodo-2-(trifluoromethyl)-; 2-Iodo-3-bromo-5-chloro-α,α,α-trifluorotoluene
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-Chloro-2-Iodobenzotrifluoride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and elemental analysis, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment and are available upon request to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Melting Point	Contact for details
Heavy Metals	<20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.