Description

2-Methyl-Pyridine-4-Sulfonyl Chloride is a versatile and highly reactive sulfonyl chloride derivative, primarily used as a key building block in organic synthesis. Its value lies in its ability to act as a sulfonylation reagent, facilitating the introduction of the sulfonyl functional group into target molecules, which is critical for modifying physicochemical properties and biological activity. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, particularly in the development of active pharmaceutical ingredients (APIs), crop protection agents, and specialty polymers.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of sulfonamide-based drugs, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the production of novel herbicides, fungicides, and insecticides where the sulfonyl moiety enhances efficacy.
• Material Science: Serves as a monomer or cross-linking agent in the development of advanced polymers and functional materials.
• Chemical Research & Development: A valuable reagent for medicinal chemistry and process chemistry for creating compound libraries and optimizing synthetic routes.
• Dye and Pigment Manufacturing: Employed in the synthesis of specialty sulfonated dyes and colorants.

Basic Information

Product Name	2-Methyl-Pyridine-4-Sulfonyl Chloride
CAS No.	1025509-77-6
Molecular Formula	C6H6ClNO2S
Molecular Weight	191.64 g/mol
Synonyms	4-(Chlorosulfonyl)-2-methylpyridine; 2-Picoline-4-sulfonyl chloride; 2-Methyl-4-pyridinesulfonyl chloride; 4-Pyridinesulfonyl chloride, 2-methyl-; 2-Methylpyridine-4-sulfonyl chloride; 2-Methyl-4-sulfonylchloropyridine
EINECS	Contact for details

Quality Control

Our 2-Methyl-Pyridine-4-Sulfonyl Chloride is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and titration methods, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.