Description

Sgi-1776 is a high-purity, small molecule compound identified by CAS No. 1025065-69-3, primarily utilized as a key research-grade intermediate and inhibitor in advanced pharmaceutical development. This compound is critical for researchers and developers focused on targeted therapeutic discovery, particularly in oncology and other disease areas involving specific enzymatic pathways. It is essential for pharmaceutical R&D laboratories, biotechnology companies, and academic research institutions engaged in preclinical studies and high-throughput screening.

Application

• Pharmaceutical Research & Development: Serves as a critical biochemical tool and reference standard in drug discovery programs.
• Preclinical Studies: Used as a potent and selective inhibitor in in vitro and in vivo pharmacological models to validate novel drug targets.
• Biochemical Assay Development: Employed as a key component in establishing high-throughput screening (HTS) assays for identifying new lead compounds.
• Chemical Biology: Acts as a molecular probe to study specific protein functions and signal transduction pathways within cells.
• Academic Research: Utilized in university and institutional labs for fundamental research in medicinal chemistry and molecular biology.
• API Intermediate Synthesis: Functions as a sophisticated building block in the multi-step synthesis of potential Active Pharmaceutical Ingredients (APIs).

Basic Information

Product Name	Sgi-1776
CAS No.	1025065-69-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Sgi1776; Sgi 1776; 5-[(5-Fluoro-2-hydroxyphenyl)methylene]-2-imino-1,3-thiazolidin-4-one; Free Base SGI-1776; PIM Kinase Inhibitor SGI-1776
EINECS	Contact for details

Quality Control

Our Sgi-1776 is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes comprehensive analytical testing, including identity confirmation by spectroscopic methods (NMR, IR, MS) and purity determination by HPLC. A Certificate of Analysis (COA) detailing all test results and specifications is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.