Description

6-Methyl-2-Oxo-2,3-Dihydro-1H-Benzimidazole-5-Sulfonyl Chloride(Saltdata: Free) is a high-purity, advanced pharmaceutical intermediate characterized by its reactive sulfonyl chloride group. This compound is critical for the synthesis of active pharmaceutical ingredients (APIs) and other fine chemicals, offering a versatile building block for medicinal chemistry. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel therapeutic agents and high-value compounds.

Application

• Key Intermediate in API Synthesis: Serves as a crucial precursor in the production of various benzimidazole-derived active pharmaceutical ingredients.
• Sulfonamide Formation: The reactive sulfonyl chloride group enables efficient coupling with amines to create sulfonamide linkages, a common pharmacophore in drug design.
• Medicinal Chemistry Research: Used in research and development for creating new chemical entities and optimizing lead compounds in drug discovery programs.
• Agrochemical Intermediate: Employed in the synthesis of novel herbicides, fungicides, and plant growth regulators.
• Dye and Pigment Manufacturing: Acts as an intermediate in the production of specialized dyes and organic pigments.
• Polymer Modification: Can be used to introduce functional groups into polymer chains for specialty material applications.

Basic Information

Product Name	6-Methyl-2-Oxo-2,3-Dihydro-1H-Benzimidazole-5-Sulfonyl Chloride(Saltdata: Free)
CAS No.	1023816-32-1
Molecular Formula	C8H7ClN2O3S
Molecular Weight	246.67 g/mol
Synonyms	6-Methyl-2-oxo-2,3-dihydro-1H-benzimidazole-5-sulfonyl chloride; 1H-Benzimidazole-5-sulfonyl chloride, 2,3-dihydro-6-methyl-2-oxo-; 6-Methyl-2-oxo-1,2-dihydro-3H-benzimidazole-5-sulfonyl chloride; 5-(Chlorosulfonyl)-6-methyl-1,3-dihydro-2H-benzimidazol-2-one; 6-Methyl-2-oxo-2,3-dihydrobenzimidazole-5-sulfonyl chloride; Free base of 1023816-32-1; Benzimidazolone sulfonyl chloride derivative
EINECS	Contact for details

Quality Control

Our 6-Methyl-2-Oxo-2,3-Dihydro-1H-Benzimidazole-5-Sulfonyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical intermediate applications. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong bases, amines, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.