Description

8-(Trifluoromethyl)Quinoline-2-Carboxylic Acid is a high-value, multifunctional heterocyclic building block prized for its unique structural and electronic properties. Its core value lies in its trifluoromethyl-substituted quinoline scaffold, which imparts enhanced metabolic stability, lipophilicity, and bioavailability to target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, serving as a critical intermediate in the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for developing potential drug candidates, particularly in oncology, anti-infective, and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group can improve activity and environmental stability.
• Material Science Research: Serves as a precursor for functional organic materials, such as ligands for catalysis or components in organic electronic devices.
• Chemical Biology & Proteomics: Employed as a molecular scaffold or tag in the design of chemical probes and enzyme inhibitors for biological pathway studies.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	8-(Trifluoromethyl)Quinoline-2-Carboxylic Acid
CAS No.	1023815-99-7
Molecular Formula	C11H6F3NO2
Molecular Weight	241.17 g/mol
Synonyms	2-Quinolinecarboxylic acid, 8-(trifluoromethyl)-; 8-Trifluoromethylquinoline-2-carboxylic acid; 8-(Trifluoromethyl)-2-quinolinecarboxylic acid; Quinoline-2-carboxylic acid, 8-(trifluoromethyl)-; 1023815-99-7
EINECS	Contact for details

Quality Control

Our 8-(Trifluoromethyl)Quinoline-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.