Description

C-(5-Trifluoromethyl-Pyridin-3-Yl)-Methylamine Dihydrochloride is a high-purity, advanced pharmaceutical intermediate characterized by its pyridine core and trifluoromethyl functionality. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) targeting a range of therapeutic areas. It is primarily sought after by R&D laboratories and production facilities in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially those requiring a substituted pyridine moiety for bioactivity.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Agrochemical Synthesis: Serves as a precursor in the development of advanced pesticides and herbicides, leveraging the stability imparted by the trifluoromethyl group.
• Ligand and Catalyst Development: Employed in the creation of novel ligands for catalysis or in metal-organic frameworks (MOFs) due to its nitrogen-containing heterocyclic structure.
• Chemical Biology Probes: Utilized to create labeled compounds or probes for studying biological pathways and target engagement.

Basic Information

Product Name	C-(5-Trifluoromethyl-Pyridin-3-Yl)-Methylamine Dihydrochloride
CAS No.	1020747-92-5
Molecular Formula	C8H9Cl2F3N2
Molecular Weight	261.07 g/mol
Synonyms	1-(5-(Trifluoromethyl)pyridin-3-yl)methanamine dihydrochloride; (5-(Trifluoromethyl)pyridin-3-yl)methanamine dihydrochloride; 3-Pyridinemethanamine, 5-(trifluoromethyl)-, dihydrochloride; 5-(Trifluoromethyl)nicotinylamine dihydrochloride; 3-(Aminomethyl)-5-(trifluoromethyl)pyridine dihydrochloride; 5-(Trifluoromethyl)-3-pyridinemethanamine dihydrochloride
EINECS	Contact for details

Quality Control

Every batch of C-(5-Trifluoromethyl-Pyridin-3-Yl)-Methylamine Dihydrochloride is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by techniques such as HPLC, NMR, and mass spectrometry is supplied with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.