Description

D,L-o-Desmethyl Venlafaxine-D6 CAS NO 1020719-35-0 is a high-purity, deuterium-labeled internal standard critical for ensuring analytical accuracy and reliability in quantitative bioanalysis. This compound is essential for researchers and quality control laboratories requiring precise measurement of its parent drug and metabolites in complex biological matrices. It is primarily utilized in pharmaceutical research, forensic toxicology, and clinical development for method validation and pharmacokinetic studies.

Application

• Internal Standard for LC-MS/MS Analysis: Used as a deuterated internal standard for the accurate quantification of venlafaxine and O-desmethylvenlafaxine (ODV) in biological samples (e.g., plasma, serum, urine).
• Pharmaceutical R&D and Bioanalysis: Supports method development and validation in pharmacokinetic (PK), pharmacodynamic (PD), and toxicokinetic studies during drug development.
• Forensic and Clinical Toxicology: Enables precise monitoring of drug levels for therapeutic drug monitoring (TDM) and in forensic investigations.
• Metabolite Studies: Aids in the research and quantification of metabolic pathways and profiles.
• Quality Control and Assurance: Serves as a critical reference material in analytical laboratories to ensure data integrity and compliance with regulatory standards (e.g., FDA, EMA).

Basic Information

Product Name	D,L-o-Desmethyl Venlafaxine-D6
CAS No.	1020719-35-0
Molecular Formula	C16H19D6NO2
Molecular Weight	269.42 g/mol
Synonyms	O-Desmethylvenlafaxine-d6; O-Demethylvenlafaxine-d6; Desvenlafaxine-d6; ODV-d6; (R/S)-1-[2-(Dimethylamino)-1-(4-hydroxy-3-methoxyphenyl)ethyl]cyclohexanol-d6; Pristiq-d6; Major Metabolite of Venlafaxine-d6
EINECS	Contact for details

Quality Control

Our D,L-o-Desmethyl Venlafaxine-D6 is manufactured under strict quality systems to ensure the high purity and isotopic enrichment required for analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing parameters such as chemical purity, isotopic purity (D-enrichment), and absence of interfering impurities. We adhere to relevant industry standards for reference materials, and custom purity grades are available to meet specific research protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing at -20°C under inert atmosphere to ensure maximum stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥98.0%
Isotopic Purity (D-enrichment)	≥98.0 atom % D
Chemical Purity (by HPLC)	≥95.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.