Description

4-Acetamidobenzenesulfonic Acid-D6 is a deuterated analog of 4-acetamidobenzenesulfonic acid, where six hydrogen atoms are replaced with the stable isotope deuterium. This deuteration is critical for applications requiring internal standards in mass spectrometry, enabling precise quantitative analysis and reducing matrix effects. It is primarily utilized by analytical laboratories and research institutions in the pharmaceutical, agrochemical, and environmental testing sectors for method development and high-accuracy measurements.

Application

• Internal Standard for LC-MS/MS: Serves as a stable isotope-labeled internal standard for the accurate quantification of sulfonamide drugs and related metabolites in complex biological matrices.
• Pharmaceutical Research: Used in pharmacokinetic and metabolic stability studies to track drug absorption, distribution, metabolism, and excretion (ADME) with high precision.
• Environmental Analysis: Enables the detection and measurement of trace levels of sulfonamide antibiotic residues in water and soil samples.
• Veterinary Drug Monitoring: Facilitates compliance testing for sulfonamide residues in food-producing animals, such as in meat, milk, and honey.
• Method Development & Validation: Provides a critical reference material for developing and validating robust analytical methods in regulatory and quality control laboratories.
• Isotope Dilution Mass Spectrometry (IDMS): Essential for achieving metrological traceability and highest accuracy in definitive analytical methods.

Basic Information

Product Name	4-Acetamidobenzenesulfonic Acid-D6
CAS No.	1020718-75-5
Molecular Formula	C8D6H3NO4S
Molecular Weight	219.25 g/mol (deuterated form)
Synonyms	4-Acetamidobenzenesulfonic Acid-d6; N-Acetylsulfanilic Acid-d6; Sulfanilic Acid N-Acetate-d6; Deuterated Sulfacetamide Related Compound; [2H6]-4-Acetamidobenzenesulfonic Acid; 4-Acetamidobenzene-2,3,5,6-d4-1-d2-sulfonic Acid; p-Acetamidobenzenesulfonic Acid-D6
EINECS	Contact for details

Quality Control

Every batch of 4-Acetamidobenzenesulfonic Acid-D6 is manufactured and tested under strict quality management systems. We guarantee high chemical and isotopic purity, with comprehensive testing including HPLC for chemical assay and NMR/MS for isotopic enrichment verification. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting batch-specific results for identity, purity, and deuterium content.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (MS)	Conforms to expected mass
Purity (HPLC)	≥ 98.0%
Isotopic Purity (Deuterium Enrichment)	≥ 98 atom % D
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.