Description

1-Bromo-2-Chloro-4,6-Difluorobenzene is a high-purity halogenated benzene derivative, serving as a critical building block in advanced organic synthesis. Its precise substitution pattern makes it an invaluable intermediate for creating complex molecules with tailored properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for fluorinated drug candidates targeting CNS disorders and oncology.
• Agrochemical Synthesis: Building block for novel herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Used in the development of fluorinated aromatic cores for electronic display materials and organic light-emitting diodes.
• Polymer Modification: Intermediate for introducing halogen and fluorine functionalities into polymer backbones to alter thermal and chemical resistance.
• Cross-Coupling Reactions: Serves as a substrate in Suzuki, Stille, and Buchwald-Hartwig amination reactions to construct biaryl and complex heterocyclic systems.
• Chemical Research & Development: Versatile reagent in academic and industrial R&D for exploring new synthetic methodologies and creating compound libraries.

Basic Information

Item	Detail
Product Name	1-Bromo-2-Chloro-4,6-Difluorobenzene
CAS No.	1020198-58-6
Molecular Formula	C6H2BrClF2
Molecular Weight	227.44 g/mol
Synonyms	2-Bromo-1-Chloro-3,5-Difluorobenzene; 4,6-Difluoro-1-Bromo-2-Chlorobenzene; 1-Bromo-2-Chloro-4,6-Difluorobenzene; 2-Chloro-1-Bromo-4,6-Difluorobenzene; Benzene, 1-bromo-2-chloro-4,6-difluoro-; (2-Chloro-4,6-difluorophenyl)bromide
EINECS	Contact for details

Quality Control

Every batch of 1-Bromo-2-Chloro-4,6-Difluorobenzene is manufactured under strict quality management systems. We provide comprehensive analytical documentation to ensure traceability and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing purity, identity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residue on Ignition	< 0.1%
Related Substances (HPLC)	Total impurities < 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.