Description

2-Phenyloxazol-5-Ylboronic Acid is a high-value boronic acid derivative and a key organoboron building block in modern synthetic chemistry. Its primary value lies in enabling efficient carbon-carbon bond formation, specifically through the Suzuki-Miyaura cross-coupling reaction, which is fundamental to constructing complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who are developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing biaryl or heterobiaryl motifs.
• Suzuki-Miyaura Cross-Coupling Reagent: Serves as a versatile coupling partner with aryl or vinyl halides to form new carbon-carbon bonds under palladium catalysis.
• Agrochemical Research: Used in the discovery and development of new herbicides, fungicides, and insecticides that require specific aromatic heterocyclic structures.
• Material Science & OLED Development: Employed in the synthesis of organic semiconductors, light-emitting materials, and other functional organic electronic components.
• Chemical Biology & Probe Synthesis: Useful for creating molecular probes and labeled compounds for biochemical and diagnostic applications.
• Academic & Contract Research: A valuable reagent for methodological development and custom synthesis in research laboratories and CROs (Contract Research Organizations).

Basic Information

Product Name	2-Phenyloxazol-5-Ylboronic Acid
CAS No.	1019927-05-9
Molecular Formula	C9H8BNO3
Molecular Weight	189.98 g/mol
Synonyms	(2-Phenyl-1,3-oxazol-5-yl)boronic acid; 2-Phenyl-5-oxazoleboronic acid; 5-Borono-2-phenyloxazole; 2-Phenyloxazole-5-boronic acid; Oxazole-5-boronic acid, 2-phenyl-; B-(2-Phenyl-5-oxazolyl)boronic acid; 1019927-05-9; 2-Phenyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)oxazole (protected form)
EINECS	Contact for details

Quality Control

Our 2-Phenyloxazol-5-Ylboronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for sensitive cross-coupling reactions. A detailed Certificate of Analysis (COA) with batch-specific data is provided with every shipment to guarantee traceability and consistency for your R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C in a dry, cool place. This compound is easily oxidized and moisture-sensitive; prolonged exposure to air or ambient humidity should be avoided to maintain purity and reactivity.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (H-NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.