Description

2-(1,1-Dioxidotetrahydro-3-Thienyl)Ethanesulfonyl Chloride is a specialized sulfonyl chloride derivative, a key reactive intermediate in advanced organic synthesis. Its value lies in its ability to act as a versatile electrophilic building block for introducing functionalized sulfonyl groups into target molecules. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex molecular scaffolds.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of sulfonamide-based drug candidates, particularly in medicinal chemistry programs targeting enzymes and receptors.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides that incorporate sulfonyl functional groups for enhanced activity.
• Chemical Biology Probes: Employed in the creation of activity-based probes (ABPs) and other chemical tools for studying biological pathways and protein function.
• Polymer Chemistry: Serves as a monomer or cross-linking agent in the development of specialty polymers with specific sulfonyl functionalities.
• Material Science Research: Utilized in the synthesis of advanced materials, such as metal-organic frameworks (MOFs) or functional surfaces, where the sulfonyl chloride group enables covalent attachment.
• Custom Synthesis & Contract Manufacturing: A key reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing complex, bespoke organic molecules for clients.

Basic Information

Product Name	2-(1,1-Dioxidotetrahydro-3-Thienyl)Ethanesulfonyl Chloride
CAS No.	1018656-49-9
Molecular Formula	C6H11ClO4S2
Molecular Weight	246.73 g/mol
Synonyms	2-(1,1-Dioxido-3-thiolanyl)ethanesulfonyl chloride; 2-(Tetrahydro-3-thienyl-1,1-dioxide)ethanesulfonyl chloride; 2-(1,1-Dioxotetrahydrothiophen-3-yl)ethanesulfonyl chloride; 3-(2-Chlorosulfonylethyl)thiolane 1,1-dioxide; 2-(1,1-Dioxidotetrahydrothiophen-3-yl)ethanesulfonyl chloride; 2-(1,1-Dioxido-3-thiolanyl)ethane-1-sulfonyl chloride
EINECS	Contact for details

Quality Control

Our 2-(1,1-Dioxidotetrahydro-3-Thienyl)Ethanesulfonyl Chloride is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for research and development applications. Each batch is analyzed using advanced techniques including HPLC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.