Description

2-(4-Fluorophenoxy)Ethanesulfonyl Chloride (Saltdata: Free) is a high-purity, reactive sulfonyl chloride derivative, a critical building block in modern organic synthesis. Its value lies in enabling the efficient introduction of the 2-(4-fluorophenoxy)ethanesulfonyl moiety, a key functional group for modulating biological activity and material properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, particularly for developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in sulfonamide-based therapeutics targeting various diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorophenoxy group enhances bioactivity and selectivity.
• Material Science Research: Serves as a monomer or cross-linking agent in the synthesis of specialized polymers, coatings, and functional materials with tailored surface properties.
• Chemical Biology Probes: Employed in the design and synthesis of activity-based probes (ABPs) and affinity labels for studying enzyme function and protein interactions.
• Ligand & Catalyst Development: Useful for creating novel ligands and organocatalysts used in asymmetric synthesis and transition metal catalysis.

Basic Information

Product Name	2-(4-Fluorophenoxy)Ethanesulfonyl Chloride (Saltdata: Free)
CAS No.	1018548-27-0
Molecular Formula	C8H8ClFO3S
Molecular Weight	238.66 g/mol
Synonyms	2-(4-Fluorophenoxy)ethanesulfonyl chloride; 2-(p-Fluorophenoxy)ethanesulfonyl chloride; 4-Fluorophenoxyethylsulfonyl chloride; 1-Chlorosulfonyl-2-(4-fluorophenoxy)ethane; Ethanesulfonyl chloride, 2-(4-fluorophenoxy)-; 1018548-27-0; 2-(4-Fluorophenoxy)ethyl sulfonyl chloride
EINECS	Contact for details

Quality Control

Our 2-(4-Fluorophenoxy)Ethanesulfonyl Chloride is produced under strict quality management protocols to ensure batch-to-batch consistency and high chemical purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to confirm identity and purity. A detailed Certificate of Analysis (COA) documenting all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.