Description

2,5-Difluoro-4-Iodopyridine is a high-value halogenated pyridine derivative, serving as a versatile and critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine and iodine substituents, makes it an essential intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs), particularly in the development of fluorinated drug candidates.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides where the difluoro-iodopyridine scaffold imparts desired biological activity.
• Material Science Precursor: Serves as a monomer or functionalization agent in the creation of specialty polymers, liquid crystals, and electronic materials.
• Cross-Coupling Reactions: The iodine atom is an excellent handle for metal-catalyzed cross-coupling reactions (e.g., Suzuki, Stille, Sonogashira) to introduce complex aryl/alkynyl groups.
• Fluorine Chemistry Research: A valuable substrate for studying nucleophilic aromatic substitution and further functionalization of fluorinated heterocycles.
• Ligand and Catalyst Development: Used to synthesize novel nitrogen-containing ligands for catalysis and coordination chemistry.

Basic Information

Item	Detail
Product Name	2,5-Difluoro-4-Iodopyridine
CAS No.	1017793-20-2
Molecular Formula	C5H2F2IN
Molecular Weight	256.98 g/mol
Synonyms	4-Iodo-2,5-difluoropyridine; 2,5-Difluoro-4-iodopyridine; 4-Iodo-2,5-difluoropyridine; Pyridine, 4-iodo-2,5-difluoro-; 1017793-20-2; 2,5-Difluoropyridin-4-yl iodide; 4-Iodo-2,5-difluoro-pyridine
EINECS	Contact for details

Quality Control

Every batch of 2,5-Difluoro-4-Iodopyridine is manufactured and tested under strict quality management systems. We ensure high purity and consistency through advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.