Description

2-Fluoro-4,6-Bis(Trifluoromethyl)Benzyl Bromide is a high-value, multi-fluorinated benzyl bromide derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine and bromine substituents, makes it an indispensable reagent for introducing fluorinated aromatic motifs, which are pivotal for modulating the physicochemical properties of target molecules. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients with enhanced metabolic stability, bioavailability, and lipophilicity.

Application

• Pharmaceutical Intermediate: Key synthon for the development of fluorinated drug candidates, particularly in oncology, CNS, and antiviral therapeutic areas.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides where fluorine atoms improve biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated aromatic cores in electronic materials, enhancing thermal stability and optical properties.
• Polymer & Resin Modification: Employed to incorporate fluorine into polymer backbones or side chains, improving chemical resistance and surface properties.
• Cross-Coupling Reactions: Acts as an electrophilic partner in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to construct complex biaryl systems.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for exploring new fluorination methodologies and creating specialized chemical libraries.

Basic Information

Product Name	2-Fluoro-4,6-Bis(Trifluoromethyl)Benzyl Bromide
CAS No.	1017778-46-9
Molecular Formula	C10H4BrF7
Molecular Weight	337.04 g/mol
Synonyms	α-Bromo-2-fluoro-α,α-bis(trifluoromethyl)-p-xylene; 1-(Bromomethyl)-2-fluoro-4,6-bis(trifluoromethyl)benzene; (2-Fluoro-4,6-bis(trifluoromethyl)phenyl)methyl bromide; 2-Fluoro-α,α-bis(trifluoromethyl)-4-(bromomethyl)toluene; 4-(Bromomethyl)-3,5-bis(trifluoromethyl)fluorobenzene
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-4,6-Bis(Trifluoromethyl)Benzyl Bromide is manufactured and tested under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.