Description

6-Fluoro-8-Quinolinesulfonyl Chloride is a specialized sulfonyl chloride derivative of the quinoline heterocycle, serving as a critical building block in advanced organic synthesis. Its primary value lies in its high reactivity as a sulfonylation reagent, enabling the efficient introduction of the 6-fluoro-8-quinolinesulfonyl moiety into target molecules. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially protease inhibitors and kinase inhibitors.
• Agrochemical Synthesis: Used in the development of new herbicides and fungicides with enhanced activity profiles.
• Material Science: Building block for creating functional polymers and advanced organic electronic materials.
• Chemical Biology: Employed as a labeling or cross-linking reagent for protein and enzyme studies.
• Dye & Pigment Industry: Intermediate for synthesizing specialized fluorinated quinoline-based dyes.
• Research & Development: Versatile reagent in academic and industrial R&D for exploring new chemical entities and reaction pathways.

Basic Information

Product Name	6-Fluoro-8-Quinolinesulfonyl Chloride
CAS No.	1016515-89-1
Molecular Formula	C9H5ClFNO2S
Molecular Weight	245.66 g/mol
Synonyms	8-Quinolinesulfonyl chloride, 6-fluoro-; 6-Fluoroquinoline-8-sulfonyl chloride; 6-Fluoro-8-quinolinesulfonylchloride; 6-Fluoro-8-sulfonylchloridequinoline; 1016515-89-1; 6-Fluoro-8-quinoline sulfonyl chloride; 6-Fluoroquinoline-8-sulfonylchloride
EINECS	Contact for details

Quality Control

Our 6-Fluoro-8-Quinolinesulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.