Description

4-Methoxy-2,3,5-Trimethylbenzenesulfonyl Chloride (Saltdata: Free) is a specialized sulfonyl chloride derivative, a key building block in advanced organic synthesis. This compound matters for its high reactivity, enabling the efficient introduction of the sulfonyl moiety to create complex molecules with tailored properties. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for synthesizing novel active ingredients and intermediates. Its specific substitution pattern offers unique steric and electronic characteristics for fine-tuning molecular interactions.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly for creating sulfonamide-based therapeutics.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and pesticides where the sulfonyl group is a key functional moiety.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced materials.
• Chemical Biology Probes: Employed in the design and synthesis of activity-based probes and molecular tags for studying biological systems.
• Dye and Pigment Manufacturing: Acts as an intermediate in the production of specialized sulfonated dyes and colorants.
• Custom Synthesis & Contract Manufacturing: A valuable reagent for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	4-Methoxy-2,3,5-Trimethylbenzenesulfonyl Chloride (Saltdata: Free)
CAS No.	1016500-29-0
Molecular Formula	C10H13ClO3S
Molecular Weight	248.72 g/mol
Synonyms	2,3,5-Trimethyl-4-methoxybenzenesulfonyl chloride; 4-Methoxy-2,3,5-trimethylbenzene-1-sulfonyl chloride; 1-(Chlorosulfonyl)-2,3,5-trimethyl-4-methoxybenzene; Mesitylene-4-methoxy-2-sulfonyl chloride (derivative); TMTMBS-Cl; 4-Methoxy-2,3,5-trimethylphenylsulfonyl chloride
EINECS	Contact for details

Quality Control

Our 4-Methoxy-2,3,5-Trimethylbenzenesulfonyl Chloride is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and titration methods, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We adhere to cGMP principles where applicable to support our clients in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (HPLC, Area %)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.