Description

1-(5-Fluoropyridin-2-Yl)Ethanol is a high-purity fluorinated pyridine derivative, serving as a critical chiral building block and intermediate in advanced organic synthesis. Its value lies in the unique reactivity imparted by the fluorine atom and the ethanol side chain, enabling precise molecular construction for complex target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients with enhanced properties.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug discovery.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atom can improve metabolic stability and bioavailability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Intermediate in the development of specialty polymers and advanced organic electronic materials.
• Chemical Biology Probes: Utilized in the creation of fluorinated probes for studying enzyme mechanisms and biological pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects requiring fluorinated heterocyclic architectures.

Basic Information

Product Name	1-(5-Fluoropyridin-2-Yl)Ethanol
CAS No.	1016227-97-6
Molecular Formula	C7H8FNO
Molecular Weight	141.14 g/mol
Synonyms	2-(1-Hydroxyethyl)-5-fluoropyridine; 5-Fluoro-2-(1-hydroxyethyl)pyridine; (5-Fluoropyridin-2-yl)methanol, methyl-; 1-(5-Fluoro-2-pyridinyl)ethanol; α-Methyl-5-fluoropyridine-2-methanol; 2-(α-Hydroxyethyl)-5-fluoropyridine; 5-Fluoro-2-pyridineethanol, α-methyl-
EINECS	Contact for details

Quality Control

Our 1-(5-Fluoropyridin-2-Yl)Ethanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high chemical purity and identity. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with every shipment to guarantee traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.