Description

(E)-3-(Dimethylamino)-1-(6-(Trifluoromethyl)-Pyridin-3-Yl)Prop-2-En-1-One is a high-value, advanced pharmaceutical intermediate characterized by its unique enone and trifluoromethylpyridine structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes due to its reactive enone moiety and fluorine substitution.
• Agrochemical Development: Serves as a precursor in the research and synthesis of novel pesticides and herbicides, leveraging the biological activity of the trifluoromethylpyridine group.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying enzyme inhibition and protein-ligand interactions.
• Material Science Research: Investigated as a monomer or precursor for specialty polymers and advanced organic materials.

Basic Information

Product Name	(E)-3-(Dimethylamino)-1-(6-(Trifluoromethyl)-Pyridin-3-Yl)Prop-2-En-1-One
CAS No.	1015078-44-0
Molecular Formula	C11H11F3N2O
Molecular Weight	244.21 g/mol
Synonyms	(E)-3-(Dimethylamino)-1-[6-(trifluoromethyl)pyridin-3-yl]prop-2-en-1-one; 1-(6-(Trifluoromethyl)pyridin-3-yl)-3-(dimethylamino)prop-2-en-1-one; (E)-3-(Dimethylamino)-1-(6-(trifluoromethyl)-3-pyridinyl)-2-propen-1-one; 3-(Dimethylamino)-1-(6-(trifluoromethyl)pyridin-3-yl)prop-2-en-1-one; CAS 1015078-44-0; Enaminone derivative; TFMP Enaminone Intermediate
EINECS	Contact for details

Quality Control

Our production of (E)-3-(Dimethylamino)-1-(6-(Trifluoromethyl)-Pyridin-3-Yl)Prop-2-En-1-One adheres to stringent quality management protocols. Every batch is analyzed using advanced chromatographic and spectroscopic techniques (HPLC, GC, NMR, MS) to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.