Description

1-(4-Fluorophenyl)-6-Methyl-1H-Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate of significant commercial and research interest. This compound serves as a critical building block in modern medicinal chemistry, enabling the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in therapeutic areas requiring complex heterocyclic scaffolds.
• Medicinal Chemistry Research: Used as a core structural motif for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• API Synthesis: Employed in the multi-step synthesis of potential Active Pharmaceutical Ingredients (APIs) targeting various disease pathways.
• Biochemical Tool Compound: Serves as a research chemical for probing biological mechanisms and enzyme interactions in vitro.
• Custom Synthesis Building Block: Supplied to contract research and manufacturing organizations (CROs/CMOs) for the production of bespoke molecules.

Basic Information

Product Name	1-(4-Fluorophenyl)-6-Methyl-1H-Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid
CAS No.	1011397-72-0
Molecular Formula	C15H10FN3O2
Molecular Weight	283.26 g/mol
Synonyms	1-(4-Fluorophenyl)-6-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid; 6-Methyl-1-(4-fluorophenyl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid; 1H-Pyrazolo[3,4-b]pyridine-4-carboxylic acid, 1-(4-fluorophenyl)-6-methyl-; 1011397-72-0; 1-(p-Fluorophenyl)-6-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of 1-(4-Fluorophenyl)-6-Methyl-1H-Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. All materials are characterized and verified using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.