Description

Mk-5108 (Vx-689) is a high-purity, small molecule compound of significant interest in advanced pharmaceutical research and development. Its primary value lies in its role as a potent and selective inhibitor, targeting specific biological pathways for therapeutic intervention. This product is essential for research institutions, biotechnology firms, and pharmaceutical companies engaged in the discovery and development of novel treatments.

Application

• Pharmaceutical Research & Development: Serves as a critical reference standard and active pharmaceutical ingredient (API) intermediate in preclinical and clinical studies.
• Biochemical Assay Development: Used as a tool compound to validate assay systems and study specific enzyme or receptor inhibition mechanisms.
• Targeted Therapy Development: Investigated for its potential in developing treatments for specific disease areas, including oncology and inflammatory disorders.
• Mechanism of Action (MoA) Studies: Employed in cellular and in-vivo models to elucidate disease pathways and therapeutic targets.
• High-Throughput Screening (HTS): Acts as a control or benchmark compound in screening libraries for drug discovery campaigns.
• Process Chemistry & Scale-Up: Used as a key intermediate for the synthesis and optimization of larger-scale API batches under GMP conditions.

Basic Information

Product Name	Mk-5108 (Vx-689)
CAS No.	1010085-13-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	VX-689; VX689; MK-5108; MK5108; (S)-N-((S)-1-Cyano-2-(4'-(2,4-dimorpholino-5H-pyrrolo[2,3-b]pyrazin-6-yl)-[1,1'-biphenyl]-4-yl)ethyl)-2-methyl-2-(methylsulfonyl)butanamide; IAP inhibitor VX-689; Birinapant analog
EINECS	Contact for details

Quality Control

Our Mk-5108 (Vx-689) is manufactured under strict quality systems to ensure batch-to-batch consistency and reliability for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (NMR, MS). A detailed Certificate of Analysis (COA) is provided with every shipment, documenting the specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.