Description

Azd-8055 is a potent and selective small-molecule inhibitor of the mammalian target of rapamycin (mTOR) kinase, a key regulator of cell growth and proliferation. This high-purity compound is essential for advanced biochemical and pharmacological research, particularly in the study of cancer signaling pathways and metabolic disorders. It is a critical reagent for pharmaceutical R&D, academic institutions, and biotechnology companies focused on oncology and metabolic disease target validation.

Application

• Biochemical Research: Used as a selective mTOR inhibitor to study the PI3K/Akt/mTOR signaling pathway in cell culture models.
• Oncology Research: A key tool compound for investigating mTOR's role in tumor cell growth, survival, and angiogenesis for potential cancer therapeutics.
• Pharmacology Studies: Employed in in vitro and in vivo studies to assess pharmacokinetics, pharmacodynamics, and efficacy of mTOR inhibition.
• Metabolic Disorder Research: Utilized to explore mTOR's involvement in cellular metabolism, nutrient sensing, and related diseases.
• Drug Discovery & Development: Serves as a reference standard and lead compound in high-throughput screening and structure-activity relationship (SAR) studies.
• Academic & Institutional Research: A fundamental reagent for basic science research into cell biology, autophagy, and aging.

Basic Information

Product Name	Azd-8055
CAS No.	1009298-09-2
Molecular Formula	C24H23N5O4
Molecular Weight	445.47 g/mol
Synonyms	AZD-8055; AZD8055; 2-Amino-8-[trans-4-(2-hydroxyethoxy)cyclohexyl]-6-(6-methoxy-3-pyridinyl)-4-methyl-pyrido[2,3-d]pyrimidin-7(8H)-one; mTOR Kinase Inhibitor AZD8055; 8-[trans-4-(2-Hydroxyethoxy)cyclohexyl]-2-amino-6-(6-methoxy-3-pyridinyl)-4-methylpyrido[2,3-d]pyrimidin-7(8H)-one
EINECS	Contact for details

Quality Control

Our Azd-8055 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurities is provided to ensure the material meets the stringent requirements for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. Due to its hygroscopic nature, the container must be kept in a dry environment and allowed to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.