Description

(2-Trifluoromethyl-Pyridin-4-Yl)-Acetic Acid CAS NO 1008737-00-5 is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both a trifluoromethyl group and a carboxylic acid moiety, makes it an essential intermediate for creating compounds with enhanced biological activity and physicochemical properties. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in areas like kinase inhibitors, anti-infectives, and central nervous system (CNS) agents.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group can improve metabolic stability and lipophilicity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalysis and material science applications.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new fluorinated heterocyclic compounds and their properties.
• Material Science Precursor: Potential use in the synthesis of functionalized materials, such as metal-organic frameworks (MOFs) or specialty polymers.

Basic Information

Product Name	(2-Trifluoromethyl-Pyridin-4-Yl)-Acetic Acid
CAS No.	1008737-00-5
Molecular Formula	C8H6F3NO2
Molecular Weight	205.14 g/mol
Synonyms	2-(2-(Trifluoromethyl)pyridin-4-yl)acetic acid; 4-Pyridineacetic acid, 2-(trifluoromethyl)-; (2-Trifluoromethyl-4-pyridyl)acetic acid; 2-(Trifluoromethyl)isonicotinic acid, reduced form; α-Carboxy-2-(trifluoromethyl)-4-pyridine; TFMPAA; 2-TFMP-4-yl-acetic Acid
EINECS	Contact for details

Quality Control

We supply (2-Trifluoromethyl-Pyridin-4-Yl)-Acetic Acid in high-purity grades suitable for research and commercial synthesis. Our products undergo rigorous quality testing to ensure batch-to-batch consistency and compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request. We adhere to strict quality management protocols to support our clients' needs in cGMP-compliant workflows where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed under an inert atmosphere if specified. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.