Description

[6-(Trifluoromethoxy)Pyridin-3-Yl]Boronic Acid is a high-value boronic acid derivative and a key building block in modern synthetic chemistry. Its core value lies in enabling the precise construction of complex molecules through reliable cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require a reliable, high-purity intermediate for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: A crucial building block in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and CNS drug research.
• Agrochemical Synthesis: Used in the development of advanced crop protection agents and herbicides, leveraging the trifluoromethoxy group for enhanced biological activity and metabolic stability.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands and catalysts used in asymmetric synthesis and other catalytic processes.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as those used in OLEDs and semiconductors, where the pyridine and boronic acid functionalities are valuable.
• Chemical Biology & Probe Development: Utilized in the creation of molecular probes and bioconjugates for studying biological systems and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences industry.

Basic Information

Product Name	[6-(Trifluoromethoxy)Pyridin-3-Yl]Boronic Acid
CAS No.	1008140-70-2
Molecular Formula	C6H5BF3NO3
Molecular Weight	206.92 g/mol
Synonyms	(6-(Trifluoromethoxy)pyridin-3-yl)boronic acid; 3-Pyridineboronic acid, 6-(trifluoromethoxy)-; 6-(Trifluoromethoxy)-3-pyridinylboronic Acid; 6-(Trifluoromethoxy)pyridine-3-boronic acid; 5-Borono-2-(trifluoromethoxy)pyridine; [6-(Trifluoromethoxy)-3-pyridyl]boronic acid
EINECS	Contact for details

Quality Control

Our [6-(Trifluoromethoxy)Pyridin-3-Yl]Boronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We support compliance with REACH and other relevant global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.