Description

1-Isobutyl-5-Methyl-1H-Pyrazole-4-Sulfonyl Chloride is a high-purity, reactive sulfonyl chloride derivative, a critical building block in modern organic synthesis. Its primary value lies in its role as a versatile sulfonylation reagent, enabling the efficient introduction of the sulfonyl functional group into target molecules. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds containing sulfonamide moieties with potential biological activity.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides where the sulfonyl group is integral to the molecule's mode of action.
• Functional Material Research: Serves as a building block for creating advanced polymers, ligands for catalysis, and specialty chemicals with tailored properties.
• Chemical Biology & Proteomics: Employed as a reactive handle for labeling or modifying biomolecules in probe development and activity-based protein profiling.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Item	Detail
Product Name	1-Isobutyl-5-Methyl-1H-Pyrazole-4-Sulfonyl Chloride
CAS No.	1006496-01-0
Molecular Formula	C9H15ClN2O2S
Molecular Weight	250.75 g/mol
Synonyms	1-Isobutyl-5-methyl-1H-pyrazole-4-sulfonyl chloride; 5-Methyl-1-(2-methylpropyl)-1H-pyrazole-4-sulfonyl chloride; 1H-Pyrazole-4-sulfonyl chloride, 1-(2-methylpropyl)-5-methyl-; 4-Sulfonyl chloride-1-isobutyl-5-methylpyrazole; 1-(Isobutyl)-5-methylpyrazole-4-sulfonyl chloride; Pyrazole-4-sulfonyl chloride derivative
EINECS	Contact for details

Quality Control

Every batch of 1-Isobutyl-5-Methyl-1H-Pyrazole-4-Sulfonyl Chloride is manufactured under strict quality management systems. We guarantee high chemical purity and lot-to-lot consistency through comprehensive analytical testing, including HPLC, NMR, and GC-MS. A detailed Certificate of Analysis (COA) providing full specification results is provided with each shipment to ensure traceability and support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.