Description

1-(2,2-Difluoroethyl)-3-Methyl-1H-Pyrazole-4-Sulfonyl Chloride is a high-purity, advanced pharmaceutical intermediate and versatile chemical building block. This compound is valued for its role as a key sulfonylating agent, enabling the synthesis of complex molecules with enhanced biological activity. It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting metabolic and central nervous system disorders.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides and fungicides, where the difluoroethyl and sulfonyl chloride groups contribute to efficacy and selectivity.
• Chemical Biology & Proteomics: Serves as a reactive handle for labeling and modifying proteins or other biomolecules in research applications.
• Material Science Research: Employed in the development of specialty polymers and functional materials that require specific sulfonamide linkages.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, specialized intermediates.

Basic Information

Product Name	1-(2,2-Difluoroethyl)-3-Methyl-1H-Pyrazole-4-Sulfonyl Chloride
CAS No.	1006462-96-9
Molecular Formula	C6H7ClF2N2O2S
Molecular Weight	244.65 g/mol
Synonyms	3-Methyl-1-(2,2-difluoroethyl)-1H-pyrazole-4-sulfonyl chloride; 1H-Pyrazole-4-sulfonyl chloride, 1-(2,2-difluoroethyl)-3-methyl-; 1-(2,2-Difluoroethyl)-3-methylpyrazole-4-sulfonyl chloride; 3-Methyl-1-(2,2-difluoroethyl)pyrazole-4-sulfonyl chloride; DFMPSC; Difluoroethyl Methyl Pyrazole Sulfonyl Chloride
EINECS	Contact for details

Quality Control

Every batch of 1-(2,2-Difluoroethyl)-3-Methyl-1H-Pyrazole-4-Sulfonyl Chloride is manufactured under strict quality management systems. We employ advanced analytical techniques, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency meet the stringent requirements of our global clientele. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.