Description

3,5-Dimethyl-1-(2,2,2-trifluoroethyl)-1H-pyrazole-4-sulfonyl chloride is a high-value, reactive sulfonyl chloride derivative, primarily utilized as a key synthetic intermediate in advanced organic chemistry. Its core value proposition lies in enabling the efficient introduction of the sulfonamide functional group, a critical motif in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries who require a reliable, high-purity building block for constructing complex molecules.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in the development of sulfonamide-based therapeutics.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the sulfonamide group confers specific biological activity.
• Chemical Research & Development: Serves as a versatile reagent in medicinal chemistry for lead optimization and structure-activity relationship (SAR) studies.
• Specialty Chemical Manufacturing: Employed in the synthesis of dyes, pigments, and functional materials requiring sulfonylation reactions.
• Process Chemistry: Valued for its reactivity in scalable manufacturing processes for active ingredients under controlled conditions.

Basic Information

Product Name	3,5-Dimethyl-1-(2,2,2-trifluoroethyl)-1H-pyrazole-4-sulfonyl chloride
CAS No.	1006462-90-3
Molecular Formula	C7H8ClF3N2O2S
Molecular Weight	276.66 g/mol
Synonyms	1H-Pyrazole-4-sulfonyl chloride, 3,5-dimethyl-1-(2,2,2-trifluoroethyl)-; 3,5-Dimethyl-1-(2,2,2-trifluoroethyl)pyrazole-4-sulfonyl chloride; 4-(Chlorosulfonyl)-3,5-dimethyl-1-(2,2,2-trifluoroethyl)-1H-pyrazole; 3,5-Dimethyl-1-(trifluoroethyl)pyrazole-4-sulfonyl chloride
EINECS	Contact for details

Quality Control

Our 3,5-Dimethyl-1-(2,2,2-trifluoroethyl)-1H-pyrazole-4-sulfonyl chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for demanding R&D and scale-up applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality systems are designed to meet the rigorous standards expected in pharmaceutical and agrochemical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.