Description

1-Butyl-5-Methyl-1H-Pyrazole-4-Sulfonyl Chloride is a versatile and reactive sulfonyl chloride derivative, primarily used as a key synthetic intermediate in advanced organic synthesis. Its core value lies in enabling the efficient introduction of the sulfonamide functional group, which is critical for modulating the biological activity and physicochemical properties of target molecules. This high-purity building block is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries engaged in the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in the development of sulfonamide-based therapeutics with potential applications in oncology, anti-infectives, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the sulfonamide moiety can enhance efficacy and environmental profile.
• Material Science Research: Serves as a precursor for creating functional polymers, dyes, and advanced materials with specific sulfonated properties.
• Chemical Biology & Proteomics: Employed as a reactive handle for bioconjugation and the development of chemical probes to study enzyme function and protein interactions.
• Custom Synthesis & Contract Manufacturing: An essential reagent for fine chemical and CDMO (Contract Development and Manufacturing Organization) facilities producing high-value, complex molecules for clients.

Basic Information

Product Name	1-Butyl-5-Methyl-1H-Pyrazole-4-Sulfonyl Chloride
CAS No.	1006454-04-1
Molecular Formula	C9H15ClN2O2S
Molecular Weight	250.75 g/mol
Synonyms	1-Butyl-5-methyl-1H-pyrazole-4-sulfonyl chloride; 4-Pyrazolesulfonyl chloride, 1-butyl-5-methyl-; 1-Butyl-5-methylpyrazole-4-sulfonyl chloride; 1-Butyl-5-methyl-1H-pyrazole-4-sulfonchlorid; 1-Butyl-5-methyl-1H-pyrazol-4-sulfonyl chloride; 1H-Pyrazole-4-sulfonyl chloride, 1-butyl-5-methyl-; 1006454-04-1
EINECS	Contact for details

Quality Control

Our 1-Butyl-5-Methyl-1H-Pyrazole-4-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.