Description

1-(5-Trifluoromethyl-2-Pyridyl)-1H-Pyrazole-4-Sulfonyl Chloride is a high-purity, advanced pharmaceutical intermediate and chemical building block. This compound is valued for its role as a key sulfonylation reagent in the synthesis of complex bioactive molecules. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in medicinal chemistry research targeting various disease pathways.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the trifluoromethylpyridyl moiety contributes to biological activity and metabolic stability.
• Chemical Biology Probe Development: Serves as a reagent for creating sulfonamide-based probes used in protein labeling and enzyme inhibition studies.
• Material Science Research: Employed in the synthesis of specialized polymers and functional materials that require sulfonyl chloride chemistry.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom chemical synthesis services catering to R&D and pilot-scale production.

Basic Information

Product Name	1-(5-Trifluoromethyl-2-Pyridyl)-1H-Pyrazole-4-Sulfonyl Chloride
CAS No.	1006441-36-6
Molecular Formula	C9H5ClF3N3O2S
Molecular Weight	311.67 g/mol
Synonyms	1-(5-(Trifluoromethyl)pyridin-2-yl)-1H-pyrazole-4-sulfonyl chloride; 1H-Pyrazole-4-sulfonyl chloride, 1-[5-(trifluoromethyl)-2-pyridinyl]-; 1-(5-Trifluoromethyl-2-pyridinyl)-1H-pyrazole-4-sulfonyl chloride; 2-(4-(Chlorosulfonyl)-1H-pyrazol-1-yl)-5-(trifluoromethyl)pyridine
EINECS	Contact for details

Quality Control

Our 1-(5-Trifluoromethyl-2-Pyridyl)-1H-Pyrazole-4-Sulfonyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.