Description

P38 Mapk-In-1 is a potent and selective small molecule inhibitor of the p38 mitogen-activated protein kinase (MAPK) signaling pathway. This compound is a critical research tool for investigating cellular stress responses, inflammation, and apoptosis in various disease models. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and biotechnology companies engaged in drug discovery and molecular biology studies. The product is supplied as a high-purity biochemical reagent to ensure reliable and reproducible experimental results.

Application

• Biochemical Research: Used as a selective inhibitor to study the role of p38 MAPK in cellular signaling cascades.
• Drug Discovery: Serves as a reference compound or lead molecule in the development of novel anti-inflammatory and anti-cancer therapeutics.
• Cell Biology Studies: Applied in vitro to elucidate mechanisms of cytokine production, cell differentiation, and stress-induced apoptosis.
• Target Validation: Employed in pharmacological experiments to validate p38 MAPK as a therapeutic target for various diseases.
• Academic Research: A key reagent for university and institutional labs focusing on kinase biology and signal transduction.

Basic Information

Product Name	P38 Mapk-In-1
CAS No.	1006378-90-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	P38 MAPK Inhibitor 1; p38 MAP Kinase Inhibitor 1; P38 MAPK-IN-1; 1006378-90-0; p38α MAPK inhibitor; p38 Mitogen-Activated Protein Kinase Inhibitor 1; MAPK14 Inhibitor
EINECS	Contact for details

Quality Control

Our P38 Mapk-In-1 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and other critical parameters is provided with every shipment to guarantee traceability and consistency for your research.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, moisture-free environment. The product is hygroscopic (moisture-sensitive) and should be handled under inert conditions when possible to ensure long-term stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Solubility	Soluble in DMSO, DMF

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.