Description

2-(3-(Trifluoromethyl)-1H-Pyrazol-1-Yl)Acetonitrile is a high-value, fluorinated pyrazole derivative building block essential for advanced organic synthesis. Its core value lies in the trifluoromethylpyrazole scaffold, which imparts desirable properties like enhanced metabolic stability and lipophilicity to target molecules. This compound is critically needed by R&D and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel drug candidates, particularly in kinase inhibitor and anti-inflammatory research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the CF3 group improves bioactivity.
• Material Science Research: Serves as a precursor for functionalized ligands and monomers in specialty polymers and advanced materials.
• Chemical Biology Probes: Employed in the synthesis of tagged molecules for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring fluorinated heterocycles.

Basic Information

Product Name	2-(3-(Trifluoromethyl)-1H-Pyrazol-1-Yl)Acetonitrile
CAS No.	1006348-71-5
Molecular Formula	C6H4F3N3
Molecular Weight	175.11 g/mol
Synonyms	1H-Pyrazole-1-acetonitrile, 3-(trifluoromethyl)-; 2-[3-(Trifluoromethyl)pyrazol-1-yl]acetonitrile; Acetonitrile, 2-[3-(trifluoromethyl)-1H-pyrazol-1-yl]-; 3-(Trifluoromethyl)-1H-pyrazole-1-acetonitrile; (3-Trifluoromethyl-1H-pyrazol-1-yl)-acetonitrile; 2-(3-Trifluoromethyl-1H-pyrazol-1-yl)acetonitrile
EINECS	Contact for details

Quality Control

Our 2-(3-(Trifluoromethyl)-1H-Pyrazol-1-Yl)Acetonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency suitable for research and scale-up. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if possible after opening to maintain quality.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.