Description

C-(4-Trifluoromethyl-Pyridin-2-Yl)Methylamine Hydrochloride is a high-purity organic salt building block featuring a pyridine core substituted with a trifluoromethyl group and an aminomethyl side chain. This compound is of significant commercial value as a versatile intermediate in the synthesis of advanced pharmaceutical and agrochemical agents. It is primarily sought after by R&D chemists and process development scientists in the life sciences sector for constructing complex molecules with enhanced biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors and central nervous system (CNS) targeted drugs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging the trifluoromethyl group for improved efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis for asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials and functional polymers where the pyridine moiety acts as a coordinating site.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and labeled compounds for biochemical and diagnostic applications.

Basic Information

Product Name	C-(4-Trifluoromethyl-Pyridin-2-Yl)Methylamine Hydrochloride
CAS No.	1005515-26-3
Molecular Formula	C8H8ClF3N2
Molecular Weight	224.61 g/mol
Synonyms	2-(Aminomethyl)-4-(trifluoromethyl)pyridine hydrochloride; (4-Trifluoromethyl-2-pyridinyl)methanamine hydrochloride; 1-(4-Trifluoromethylpyridin-2-yl)methanamine hydrochloride; α-Amino-4-(trifluoromethyl)-2-picoline hydrochloride; 2-Pyridinemethanamine, 4-(trifluoromethyl)-, hydrochloride; 4-(Trifluoromethyl)pyridin-2-ylmethylamine HCl; (4-Trifluoromethyl-pyridin-2-yl)-methylamine HCl
EINECS	Contact for details

Quality Control

Our C-(4-Trifluoromethyl-Pyridin-2-Yl)Methylamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring material of pharmaceutical and research grade purity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.