Description

Lcl-161 CAS NO 1005342-46-0 is a high-purity chemical compound used as a critical intermediate in advanced pharmaceutical research and development. This compound is valued for its role in the synthesis of novel therapeutic agents, particularly in targeted drug discovery programs. It is primarily sought by research institutions, pharmaceutical companies, and biotechnology firms engaged in medicinal chemistry and preclinical studies.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of investigational new drugs (INDs) and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for novel therapeutic targets.
• Biochemical Tool Compound: Employed in vitro and in vivo to study specific biological pathways and mechanisms of action.
• Preclinical Development: Serves as a critical material for pharmacokinetic, pharmacodynamic, and toxicology studies.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and development services.
• Academic Research: Utilized in university laboratories for cutting-edge chemical biology and drug discovery projects.

Basic Information

Product Name	Lcl-161
CAS No.	1005342-46-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Lcl161; LCL 161; LCL-161; 1005342-46-0; SMAC mimetic LCL161; (S,R)-LCL161; IAP Inhibitor LCL161; Birinapant analog; Second mitochondria-derived activator of caspases mimetic.
EINECS	Contact for details

Quality Control

Our Lcl-161 is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical characterization using techniques such as HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and related substances is provided with every shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.