Description

3-Fluoro-4-Iodobenzaldehyde is a versatile halogenated aromatic aldehyde building block, distinguished by its unique combination of fluorine and iodine substituents. This compound is critical for introducing specific electronic and steric properties into target molecules, enabling precise tuning of material and biological activity. It is primarily sought after by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for applications in medicinal chemistry, ligand synthesis, and the development of organic electronic components.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the creation of novel herbicides, fungicides, and pesticides, leveraging the halogen atoms for bioactivity and metabolic stability.
• Ligand & Catalyst Development: Serves as a precursor for sophisticated ligands in transition metal catalysis and organocatalysis.
• Material Science: Employed in the synthesis of organic semiconductors, liquid crystals, and photoactive polymers.
• Chemical Biology: Useful as a probe or labeling reagent due to the reactivity of the aldehyde group and the presence of the iodine atom for further functionalization.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to build complex biaryl systems.

Basic Information

Product Name	3-Fluoro-4-Iodobenzaldehyde
CAS No.	1003709-57-6
Molecular Formula	C7H4FIO
Molecular Weight	249.99 g/mol
Synonyms	4-Iodo-3-fluorobenzaldehyde; 3-Fluoro-4-iodo-benzaldehyde; Benzaldehyde, 3-fluoro-4-iodo-; 3-Fluoro-p-iodobenzaldehyde; 4-Formyl-2-fluoro-1-iodobenzene; 2-Fluoro-4-formyl-1-iodobenzene; 1-Iodo-2-fluoro-4-formylbenzene
EINECS	Contact for details

Quality Control

Our 3-Fluoro-4-Iodobenzaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Melting Point	Contact for details
Heavy Metals	<20 ppm
Residue on Ignition	<0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.