Description

Srt1720 is a high-purity chemical compound identified by CAS No. 1001645-58-4. This compound is valued for its role as a potent and selective activator of SIRT1, a key enzyme involved in cellular metabolism and stress response pathways. It is primarily utilized by researchers and developers in the pharmaceutical and life science sectors for metabolic disease research, aging studies, and the development of novel therapeutic agents.

Application

• Pharmaceutical Research & Development: As a key reference standard and active pharmaceutical ingredient (API) intermediate in metabolic and aging-related drug discovery programs.
• Biochemical Research: Used as a potent tool compound in vitro and in vivo to study SIRT1-mediated pathways, including glucose homeostasis, insulin sensitivity, and mitochondrial biogenesis.
• Preclinical Studies: Investigation of therapeutic potential for conditions such as type 2 diabetes, obesity, and age-associated metabolic disorders.
• Academic Research: Fundamental research into sirtuin biology, calorie restriction mimetics, and cellular senescence.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	Srt1720
CAS No.	1001645-58-4
Molecular Formula	C25H28N6O2
Molecular Weight	444.53 g/mol
Synonyms	SRT1720; SRT-1720; 1,4-Dihydro-2,6-dimethyl-4-(2-trifluoromethylphenyl)-3,5-pyridinedicarboxylic acid 2-methoxyethyl (1-methylethyl) ester; N-(2-(3-(piperazin-1-ylmethyl)imidazo[2,1-b]thiazol-6-yl)phenyl)quinoxaline-2-carboxamide; Sirtuin 1 activator SRT1720
EINECS	Contact for details

Quality Control

Our Srt1720 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with each shipment, ensuring traceability and compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.