Description

3-(Trifluoromethyl)Piperidin-2-One is a high-value fluorinated heterocyclic building block, distinguished by the presence of a trifluoromethyl group on the piperidone ring. This compound is critical for medicinal chemistry and agrochemical research, where its unique electronic and steric properties are leveraged to modulate the bioavailability, metabolic stability, and potency of target molecules. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the development of central nervous system (CNS) active drugs, enzyme inhibitors, and receptor modulators.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the CF3 group enhances lipophilicity and biological activity.
• Material Science Research: Serves as a precursor for specialty polymers and liquid crystals that require fluorinated components for specific thermal or chemical resistance properties.
• Chemical Biology Probes: Employed in the design of molecular probes and tags for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: A vital building block for custom synthesis houses serving the pharmaceutical and biotechnology industries.

Basic Information

Product Name	3-(Trifluoromethyl)Piperidin-2-One
CAS No.	1000934-03-1
Molecular Formula	C6H8F3NO
Molecular Weight	167.13 g/mol
Synonyms	3-(Trifluoromethyl)-2-piperidone; 3-(Trifluoromethyl)piperidin-2-one; 2-Piperidinone, 3-(trifluoromethyl)-; 3-Trifluoromethyl-2-piperidone; 3-Trifluoromethylpiperidin-2-one; 3-(Trifluoromethyl)-2-piperidinone; 3-(Trifluoromethyl)-2-oxopiperidine
EINECS	Contact for details

Quality Control

Every batch of 3-(Trifluoromethyl)Piperidin-2-One is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.