Description

Methyl 4-Chloro-3-(Chlorosulfonyl)Benzoate is a high-purity, multi-functional organic intermediate of significant importance in advanced chemical synthesis. Its core value lies in its dual reactive sites—the chlorosulfonyl and ester groups—which enable precise and versatile derivatization. This compound is primarily needed by R&D and production chemists in the pharmaceutical and agrochemical industries for constructing complex molecular architectures, such as active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, leveraging the chlorosulfonyl group for potent biological activity.
• Material Science Research: Serves as a precursor for functional monomers or cross-linking agents in the development of specialty polymers.
• Dye and Pigment Intermediate: Facilitates the introduction of sulfonyl chloride functionality into complex dye molecules for enhanced properties.
• Custom Chemical Synthesis: Employed in contract research and manufacturing (CRAM) for bespoke, small-molecule library development and scale-up projects.

Basic Information

Product Name	Methyl 4-Chloro-3-(Chlorosulfonyl)Benzoate
CAS No.	1000933-19-6
Molecular Formula	C8H6Cl2O4S
Molecular Weight	269.10 g/mol
Synonyms	4-Chloro-3-(chlorosulfonyl)benzoic acid methyl ester; Methyl 4-chloro-3-chlorosulfonylbenzoate; Benzoic acid, 4-chloro-3-(chlorosulfonyl)-, methyl ester; 3-(Chlorosulfonyl)-4-chlorobenzoic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 4-Chloro-3-(Chlorosulfonyl)Benzoate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, to meet the stringent requirements of advanced synthetic applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.