Description

1,2-Dibromo-4-Chloro-5-Fluoro-Benzene is a highly functionalized halogenated benzene derivative, serving as a critical multi-purpose building block in advanced organic synthesis. Its precise halogen substitution pattern makes it an indispensable intermediate for constructing complex molecules where regioselective functionalization is paramount. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially in fluorinated drug candidates.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the halogen pattern confers specific biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and material science.
• Functional Material Research: Employed in the development of organic electronic materials, liquid crystals, and polymers requiring specific halogen interactions.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis houses serving the life sciences sector.
• Academic and Industrial R&D: Used in research laboratories for method development and exploring new chemical spaces in heterocyclic and fluorinated chemistry.

Basic Information

Product Name	1,2-Dibromo-4-Chloro-5-Fluoro-Benzene
CAS No.	1000578-16-4
Molecular Formula	C6H2Br2ClF
Molecular Weight	308.24 g/mol
Synonyms	4-Chloro-1,2-dibromo-5-fluorobenzene; 5-Fluoro-1,2-dibromo-4-chlorobenzene; 1,2-Dibromo-4-chloro-5-fluorobenzene; Benzene, 1,2-dibromo-4-chloro-5-fluoro-; 4-Chloro-5-fluoro-1,2-dibromobenzene
EINECS	Contact for details

Quality Control

Our 1,2-Dibromo-4-Chloro-5-Fluoro-Benzene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and elemental analysis, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our quality commitment ensures the material meets the stringent requirements for R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Ensure the container is kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.